Questionnaire-Description

The MSQOL-25 is a 25-item questionnaire designed to measure the impact of migraines on various aspects of an individual’s life. The questions cover three main areas:
Functional status: The impact of migraines on the ability to perform daily activities.
Emotional status: The psychological and emotional burden related to migraines.
Physical health: The physical effects of migraines on health and vitality.
The MSQOL-25 recognizes the significant impact migraines have on quality of life and allows researchers and healthcare professionals to understand how these affect various aspects of daily living.

Data Analysis and Usage

The data collected from the MSQOL-25 are analyzed to depict the effects of migraines on patients’ lives. Responses are typically scored on a Likert scale, where participants rate the extent to which migraines affect their daily activities and overall well-being.
Data analyses applied include:
Reliability analysis, such as calculating Cronbach’s alpha, to ensure the stability of responses.
Factor analysis to confirm the dimensions included in the questionnaire.
Correlation analysis to study the relationship between migraine frequency or severity and quality of life.
The data can be used in clinical studies to evaluate the effectiveness of drugs or other therapies aimed at improving the quality of life for individuals with migraines.

Purpose

The main goal of the Migraine-Specific Quality-of-Life (MSQOL-25) is to assess the impact of migraines on the quality of life of those experiencing them. Specifically, the scale helps understand:
The extent of the impact of migraines on daily life.
The emotional and psychological burdens caused by migraines.
The physical incapacity and limitations migraines impose on daily activities.
The MSQOL-25 is used to monitor the quality of life of migraine patients during therapeutic interventions or in studies evaluating the severity of the condition.

Calibration

The calibration of the MSQOL-25 involves the following stages:
Reliability analysis to measure the internal consistency of the scale and ensure response stability.
Factor analysis to confirm the key domains affected by migraines.
Cross-validation of the scale across different populations to ensure the validity and generalizability of the results to various patient groups.

Bibliography

Jhingran, P., Osterhaus, J. T., Miller, D. W., Lee, J. T., & Kirchdoerfer, L. (1998). Development and validation of the migraine-specific quality of life questionnaire. Headache: The Journal of Head and Face Pain, 38(4), 295-302.
Bagley, C. L., Rendas-Baum, R., Maglinte, G. A., Yang, M., Varon, S. F., & Lee, J. T. (2012). Validating Migraine-Specific Quality of Life Questionnaire v2.1 in episodic and chronic migraine. Headache: The Journal of Head and Face Pain, 52(3), 409-421.
Lipton, R. B., Stewart, W. F., Kolodner, K., Sawyer, J., & Liberman, J. N. (2003). Migraine impact and treatment patterns: Insights from the American Migraine Study II. Headache: The Journal of Head and Face Pain, 43(5), 624-631.