Questionnaire-Description

The INQLQ-45 is an assessment tool targeted at individuals with neuromuscular disorders such as muscular dystrophy, amyotrophic lateral sclerosis (ALS), or other conditions affecting the neuromuscular system. The questionnaire consists of 45 items and aims to evaluate the patients’ quality of life in various domains such as:
Physical function
Emotional well-being
Social interaction
Levels of independence
Pain and discomfort
This scale is individualized, allowing it to adapt to the specific needs and priorities of each individual, making it especially useful in settings where personalized assessments of quality of life are needed.

Data Analysis and Usage

Data from the INQLQ-45 is collected through questionnaires where participants are asked to rate various aspects of their life using Likert scales. The responses are analyzed to identify the areas where patients face the most challenges and to monitor disease progression or response to treatment.
Statistical analyses such as:
Factor analysis is used to identify the main dimensions that affect patients’ quality of life.
Reliability analysis to measure the internal consistency of the scale.
Comparative analysis to study differences in quality of life between different patient subgroups or throughout the course of the disease.

Purpose

The goal of the INQLQ-45 is to provide an accurate and comprehensive assessment of the quality of life in individuals with neuromuscular disorders. This tool helps healthcare professionals better understand the specific challenges faced by patients and develop personalized treatment plans. Additionally, the INQLQ-45 can be used to evaluate the effectiveness of therapeutic interventions over time.

Calibration

Calibration of the INQLQ-45 is conducted using standard psychometric techniques:
Reliability analysis, with the calculation of Cronbach’s alpha to assess the internal consistency of the questionnaire items.
Confirmatory factor analysis to ensure the validity of the scale and its applicability to different populations.
Cross-validation to confirm the scale’s reliability across various environments and patient groups.

Bibliography

Abresch, R. T., Carter, G. T., Jensen, M. P., & Kilmer, D. D. (2002). Assessment of quality of life in neuromuscular disease. American Journal of Physical Medicine & Rehabilitation, 81(3), 162-171.
Hobart, J. C., & Cano, S. J. (2009). Improving the evaluation of therapeutic interventions in multiple sclerosis: The role of new psychometric methods. Health Technology Assessment, 13(12), iii, ix-x, 1-177.
Carter, G. T., & Abresch, R. T. (2004). Quantitative measures and clinical trial design in neuromuscular disease. Physical Medicine and Rehabilitation Clinics of North America, 15(4), 951-969.